2012 (v1)
Publication
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Uploaded on: April 14, 2023
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Last name: GIAN PAOLO TONINI
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The RNA-binding protein LIN28B regulates developmental timing and determines stem cell identity by suppressing the let-7 family of microRNAs. Postembryonic reactivation of LIN28B impairs cell commitment to differentiation, prompting their transformation. In this study, we assessed the extent to which ectopic lin28b expression modulates the...