In the last decades, there was an important paucity of agents for adequately treating infections due to metallo-beta-lactamases-producing Gram-negative bacteria (MBL-GNB). Cefiderocol, a novel siderophore cephalosporin showing in vitro activity against MBL-GNB, has been recently marketed, and a combination of aztreonam and ceftazidime/avibactam...
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2020 (v1)PublicationUploaded on: April 14, 2023
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2017 (v1)Publication
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Uploaded on: April 14, 2023 -
2022 (v1)Publication
Carbapenemase-producing Enterobacterales (CPE) represent a major cause of difficult-to-treat infections worldwide. The novel β-lactam/β-lactamase inhibitor combinations (BLICs), including ceftazidime/avibactam (CZA), meropenem/vaborbactam (MVB), and imipenem/relebactam (IMR), represented a breakthrough to treat some CPE infections. However,...
Uploaded on: February 14, 2024 -
2017 (v1)Publication
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Uploaded on: April 14, 2023