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GIANNI , Luca

Last name: GIANNI

First name: Luca

2018 (v1)

Publication

Metadata-only

Neoadjuvant treatment with trastuzumab and pertuzumab plus palbociclib and fulvestrant in HER2-positive, ER-positive breast cancer (NA-PHER2): An exploratory, open-label, phase 2 study

Gianni, Luca Bisagni, Giancarlo Colleoni, Marco

Background: In the neoadjuvant setting, blockade of HER2 plus use of an aromatase inhibitor in patients with HER2-positive and oestrogen receptor (ER)-positive breast cancer leads to a pathological complete response in 21% of patients. Convergence of HER2 and ER signals on RB1 suggests that a combined pharmacological intervention directed to...

Uploaded on: April 14, 2023