Most patients with idiopathic REM sleep behavior disorder (iRBD) will develop an overt alpha-synucleinopathy over time, with a rate of phenoconversion of 73.5% after 12 years from diagnosis. Several markers of phenoconversion were identified; however, most studies investigated biomarkers separately, with retrospective study designs, in small...
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2022 (v1)PublicationUploaded on: February 13, 2024
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2023 (v1)Publication
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Uploaded on: February 13, 2024 -
2022 (v1)Publication
Introduction Narcolepsy is a chronic and rare hypersomnia of central origin characterized by excessive daytime sleepiness and a complex array of symptoms as well as by several medical comorbidities. With growing pharmacological options, polytherapy may increase the possibility of a patient-centered management of narcolepsy symptoms. The aims of...
Uploaded on: December 16, 2023