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GIUNCO , Silvia

Last name: GIUNCO

First name: Silvia

July 25, 2020 (v1)

Journal article

Metadata-only

Anti-Proliferative and Pro-Apoptotic Effects of Short-Term Inhibition of Telomerase In Vivo and in Human Malignant B Cells Xenografted in Zebrafish

Giunco, Silvia Zangrossi, Manuela Dal Pozzolo, Francesca

Besides its canonical role in stabilizing telomeres, telomerase reverse transcriptase (TERT) may promote tumor growth/progression through extra-telomeric functions. Our previous in vitro studies demonstrated that short-term TERT inhibition by BIBR1532 (BIBR), an inhibitor of TERT catalytic activity, negatively impacts cell proliferation and...

Uploaded on: December 4, 2022