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GOMBOS , Andrea

Last name: GOMBOS

First name: Andrea

2021 (v1)

Publication

Metadata-only

Body Mass Index and Weight Change in Patients With HER2-Positive Early Breast Cancer: Exploratory Analysis of the ALTTO BIG 2-06 Trial

Martel, Samuel Lambertini, Matteo Agbor-Tarh, Dominique

The association between obesity and prognosis in HER2-positive early breast cancer remains unclear, with limited data available. This study aimed to determine the impact of body mass index (BMI) at baseline and weight change after 2 years on outcomes of patients with HER2-positive early breast cancer.

Uploaded on: April 14, 2023
2021 (v1)

Publication

Metadata-only

Genomic and transcriptomic analyses of breast cancer primaries and matched metastases in AURORA, the Breast International Group (BIG) molecular screening initiative

Aftimos, Philippe Oliveira, Mafalda Irrthum, Alexandre

AURORA aims to study the processes of relapse in metastatic breast cancer (MBC) by performing multi-omics profiling on paired primary tumors and early-course metastases. Among 381 patients (primary tumor and metastasis pairs: 252 TGS, 152 RNA-Seq, 67 SNP Arrays), we found a driver role for GATA1 and MEN1 somatic mutations. Metastases were...

Uploaded on: March 27, 2023