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GOMEZ-BOUGIE , Patricia

Last name: GOMEZ-BOUGIE

First name: Patricia

July 25, 2016 (v1)

Journal article

Metadata-only

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

Hamouda, Mohamed Amine Jacquel, Arnaud Robert, Guillaume

Multiple myeloma (MM) evolves from a premalignant condition known as monoclonal gammopathy of undetermined significance (MGUS). However, the factors underlying the malignant transformation of plasmocytes in MM are not fully characterized. We report here that Eµ-directed expression of the antiapoptotic Bcl-B protein in mice drives an MM...

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