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GONZÁLEZ BASALLOTE , Víctor M.

Last name: GONZÁLEZ BASALLOTE

First name: Víctor M.

June 25, 2020 (v1)

Publication

Metadata-only

UAP56/DDX39B is a major cotranscriptional RNA–DNA helicase that unwinds harmful R loops genome-wide

Pérez Calero, Carmen Bayona Feliu, Aleix Xue, Xiaoyu

Nonscheduled R loops represent a major source of DNA damage and replication stress. Cells have different ways to prevent R-loop accumulation. One mechanism relies on the conserved THO complex in association with cotranscriptional RNA processing factors including the RNA-dependent ATPase UAP56/DDX39B and histone modifiers such as the SIN3...

Uploaded on: December 4, 2022