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2003 (v1)Journal articleUploaded on: December 3, 2022
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2003 (v1)Journal article
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Uploaded on: October 11, 2023 -
2003 (v1)Journal article
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Uploaded on: October 11, 2023 -
2003 (v1)Journal article
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Uploaded on: December 3, 2022 -
2005 (v1)Journal article
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Uploaded on: October 11, 2023 -
2005 (v1)Journal article
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March 2013 (v1)Journal article
The resistance of hypoxic cells to radiotherapy and chemotherapy is a major problem in the treatment of cancer. Recently, an additional mode of hypoxia-inducible factor (HIF)-dependent transcriptional regulation, involving modulation of a specific set of micro RNAs (miRNAs), including miR-210, has emerged. We have recently shown that HIF-1...
Uploaded on: December 4, 2022 -
March 14, 2010 (v1)Journal article
Targeting cancer cell metabolism is a new promising strategy to fight cancer. Metformin, a widely used antidiabetic agent, exerts antitumoral and antiproliferative action. In this study, the addition of metformin to 2-deoxyglucose (2DG) inhibited mitochondrial respiration and glycolysis in prostate cancer cells leading to a severe depletion in...
Uploaded on: December 4, 2022 -
October 1, 2010 (v1)Journal article
Following the identification of a set of hypoxia-regulated microRNAs (miRNAs), recent studies have highlighted the importance of miR-210 and of its transcriptional regulation by the transcription factor hypoxia-inducible factor-1 (HIF-1). We report here that miR-210 is overexpressed at late stages of non-small cell lung cancer. Expression of...
Uploaded on: December 4, 2022