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GOVAERTS , Anne Sophie

Last name: GOVAERTS

First name: Anne Sophie

2021 (v1)

Journal article

Metadata-only

A phase II study of monalizumab in patients with recurrent/metastatic squamous cell carcinoma of the head and neck: The I1 cohort of the EORTC-HNCG-1559 UPSTREAM trial

Galot, Rachel Le Tourneau, Christophe Saada-Bouzid, Esma

Purpose: Monalizumab is a monoclonal antibody targeting the inhibitory natural killer group 2A (NKG2A) receptor localised on natural killer (NK) and T cells. Its ligand, the human leukocyte antigen E (HLA-E), is overexpressed in squamous cell carcinoma of the head and neck (SCCHN). By targeting the HLA-E-NKG2A pathway, monalizumab may enhance...

Uploaded on: December 3, 2022