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GRANIER , Clémence

Last name: GRANIER

First name: Clémence

December 2, 2019 (v1)

Journal article

Metadata-only

HVEM has a broader expression than PD-L1 and constitutes a negative prognostic marker and potential treatment target for melanoma

Malissen, Nausicaa Macagno, Nicolas Granjeaud, Samuel

HVEM (Herpes Virus Entry Mediator) engagement of BTLA (B and T Lymphocyte Attenuator) triggers inhibitory signals in T cells and could play a role in evading antitumor immunity. Here, HVEM expression levels in melanoma metastases were analyzed by immunohistochemistry, correlated with overall survival (OS) in 116 patients, and validated by TCGA...

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