GRATTAGLIANO , Ignazio

The Doppelganger phenomenon refers to the experience of a direct encounter with one's self, characteriswed by: (i) the perception of a figure with one's own identical physical features; or (ii) the apprehension that the perceived figure shares the same personality and identity. The Doppelganger does not only look like the same person, it is...

To investigate in vitro the therapeutic effect and mechanisms of silybin in a cellular model of hepatic steatosis.

Mitochondria are not only the main energy source in the hepatocytes but also play a major role in the cell redox homeostasis and maintain normal liver function including signalling pathways and the metabolism of exogenous substances. These roles assign mitochondria a gateway function in protecting hepatocyte from injury since unbalanced...

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the excessive accumulation of triglycerides in hepatocytes. NAFLD is the most frequent chronic liver disease in developed countries, and is often associated with metabolic disorders such as obesity and type 2 diabetes. NAFLD definition encompasses a spectrum of chronic...