The biological activities of essential oils from three plants grown in Cameroon: Ocimum basilicum, Ocimum canum, and Cymbopogon citratus were tested against Plasmodium falciparum and mature-stage larvae of Anopheles funestus. Gas chromatography and gas chromatography - mass spectrometry analyses showed that the main compounds are geranial,...
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September 7, 2014 (v1)Journal articleUploaded on: February 28, 2023
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November 2019 (v1)Journal article
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October 18, 2019 (v1)Journal article
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April 2020 (v1)Journal article
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June 2021 (v1)Journal article
We previously showed that injection of recombinant human group IIA secreted phospholipase A2 (hGIIA sPLA2) to Plasmodium chabaudi-infected mice lowers parasitaemia by 20%. Here, we show that transgenic (TG) mice overexpressing hGIIA sPLA2 have a peak of parasitaemia about 30% lower than WT littermates. During infection, levels of circulating...
Uploaded on: December 4, 2022