GRUART , Agnès

Last name: GRUART

First name: Agnès

July 18, 2019 (v1)

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Mouse Nr2f1 haploinsufficiency unveils new pathological mechanisms of a human optic atrophy syndrome

Bertacchi, Michele Gruart, Agnès Kaimakis, Polynikis

Optic nerve atrophy represents the most common form of hereditary optic neuropathies leading to vision impairment. The recently described Bosch-Boonstra-Schaaf optic atrophy (BBSOA) syndrome denotes an autosomal dominant genetic form of neuropathy caused by mutations or deletions in the NR2F1 gene. Herein, we describe a mouse model...

Uploaded on: December 4, 2022
February 7, 2024 (v1)

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Chronic adult-onset of growth hormone/IGF-I hypersecretion improves cognitive functions and LTP and promotes neuronal differentiation in adult rats

Martín Rodríguez, Juan Francisco Ramos Herrero, Víctor Darío Parras, Gloria G.

Aim Besides their metabolic and endocrine functions, the growth hormone (GH) and its mediated factor, the insulin-like growth factor I (IGF-I), have been implicated in different brain functions, including neurogenesis. Long-lasting elevated GH and IGF-I levels result in non-reversible somatic, endocrine and metabolic morbidities. However, the...

Uploaded on: February 11, 2024
February 18, 2020 (v1)

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Palmitate is increased in the cerebrospinal fluid of obese humans and induces memory impairment in mice via pro-inflammatory TNF-α

Melo, Helen da S Seixas da Silva, Gisele Sant'Ana, Marcella

International audience

Uploaded on: December 4, 2022
February 2020 (v1)

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Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α

Melo, Helen Seixas da Silva, Gisele da S. Sant'ana, Marcella Ramos

International audience

Uploaded on: December 4, 2022

GRUART , Agnès

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