GUÉGNARD , Fabrice

Because the control of parasitic nematodes of livestock mainly relies on anthelmintics, the development of resistance represents a major concern. In this context, the bioactive compounds from macro-algae and their putative anthelmintic and/or biostimulant properties offer attractive perspectives for the development of alternatives to control...

Session 1 : Résistance des Helminthes et nouvelles cibles thérapeutiques

Session : Posters

The current control of gastrointestinal (GI) parasitic nematodes mainly relies on the widespread use of anthelmintics, which has inevitably led to resistance. Therefore, there is an urgent need to find new sources of antiparasitic compounds. Macroalgae represent a rich source of active molecules and are widely described as having medicinal...

Cholinergic agonists such as levamisole and pyrantel are widely used as anthelmintics to treat parasitic nematode infestations. These drugs elicit spastic paralysis by activating acetylcholine receptors (AChRs) expressed in nematode body wall muscles. In the model nematode Caenorhabditis elegans, genetic screens led to the identification of...

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