December 2017 (v1)
Journal article
Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma
While molecular subtypes of glioblastoma (GBM) are defined using gene expression and mutation profiles,we identify a unique subpopulation based on addiction to the high-affinity glucose transporter, Glut3.Although Glut3 is a known driver of a cancer stem cell phenotype, direct targeting is complicated by itsexpression in neurons. Using...
Uploaded on: March 31, 2023