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GUARNACCIA A.

Last name: GUARNACCIA A.

2022 (v1)

Publication

Metadata-only

Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients

Mantovani S. Daga S. Fallerini C.

Toll-like receptors (TLR) are crucial components in the initiation of innate immune responses to a variety of pathogens, triggering the production of pro-inflammatory cytokines and type I and II interferons, which are responsible for innate antiviral responses. Among the different TLRs, TLR7 recognizes several single-stranded RNA viruses...

Uploaded on: February 4, 2024