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J

GUEGAN , Jean-Philippe

Last name: GUEGAN

First name: Jean-Philippe

April 8, 2022 (v1)

Publication

Metadata-only

Abstract 2578: High regulatory T cells infiltrate within tertiary lymphoid structure restricts response to immune checkpoint blockers in sarcomas

Peyraud, Florent Guegan, Jean-Philippe Rey, Christophe

Abstract Background: While composition of the tumor microenvironment (TME) is a prerequisite for an effective antitumor immunity, infiltration of organized B- and T-cells aggregates called tertiary lymphoid structures (TLS) has been recently demonstrated to predict response to immune checkpoint blockers (ICB) in sarcomas. However, only a...

Uploaded on: September 12, 2024