G

A

GUERREIRO , Ana

Last name: GUERREIRO

First name: Ana

March 10, 2022 (v1)

Publication

Metadata-only

Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment

Bermejo, Iris A Navo, Claudio D. Castro López, Jorge

The Tn antigen (GalNAc-α-1-O-Thr/Ser) is a well-known tumor-associated carbohydrate determinant. The use of glycopeptides that incorporate this structure has become a significant and promising niche of research owing to their potential use as anticancer vaccines. Herein, the conformational preferences of a glycopeptide with an unnatural Tn...

Uploaded on: December 5, 2022