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J

GUILLON , Jean

Last name: GUILLON

First name: Jean

August 8, 2023 (v1)

Journal article

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Synthesis and Antimalarial Evaluation of New 1,3,5-tris[(4-(Substituted-aminomethyl)phenyl)methyl]benzene Derivatives: A Novel Alternative Antiparasitic Scaffold

Albenque-Rubio, Sandra Guillon, Jean Cohen, Anita

A series of new 1,3,5-tris[(4-(substituted-aminomethyl)phenyl)methyl]benzene compounds were designed, synthesized, and evaluated in vitro against two parasites (Plasmodium falciparum and Leishmania donovani). The biological results showed antimalarial activity with IC50 values in the sub and μM range. The in vitro cytotoxicity of these new aza...

Uploaded on: September 25, 2024
July 2024 (v1)

Conference paper

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Design, Synthesis of New 1,3,5-tris[(4-(Substituted-aminomethyl)phenoxy)methyl]benzenes and Evaluation of their Antimalarial Activity

Albenque-Rubio, Sandra Guillon, Jean Cohen, A.

International audience

Uploaded on: August 6, 2024
2024 (v1)

Journal article

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Design, Synthesis and in vitro Antimalarial Evaluation of New 1,3,5-tris[(4-(Substituted-Aminomethyl)Phenoxy)methyl]benzenes

Albenque-Rubio, Sandra Guillon, Jean Agnamey, Patrice

International audience

Uploaded on: August 2, 2024