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GUILLOT , Aline

Last name: GUILLOT

First name: Aline

September 2021 (v1)

Journal article

Metadata-only

TAXOMET: A French Prospective Multicentric Randomized Phase II Study of Docetaxel Plus Metformin Versus Docetaxel Plus Placebo in Metastatic Castration-Resistant Prostate Cancer

Pujalte Martin, Marc Borchiellini, Delphine Thamphya, Brice

Background: Docetaxel (DOCE) is a standard of care in metastatic castration-resistant prostate cancer (mCRPC). Several retrospective studies suggested a decrease in Prostate Cancer incidence and mortality with metformin (MET). MET has also demonstrated anti-tumor activity in Prostate Cancer preclinical models, with increased apoptosis when...

Uploaded on: December 4, 2022
September 17, 2021 (v1)

Journal article

Metadata-only

TAXOMET : A French prospective multicentric randomized controlled phase II study comparing docetaxel plus metformin versus docetaxel plus placebo in mCRPC

Pujalte Martin, Marc Borchiellini, Delphine Thamphya, Brice

Background: Docetaxel (DOCE) is a standard of care in metastatic castration-resistant prostate cancer (mCRPC). Several retrospective studies suggested a decrease in Prostate Cancer incidence and mortality with metformin (MET). MET has also demonstrated anti-tumor activity in Prostate Cancer preclinical models, with increased apoptosis when...

Uploaded on: December 4, 2022