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GUIMARD , Carole

Last name: GUIMARD

First name: Carole

November 2, 2022 (v1)

Publication

Metadata-only

Efficient synthetic strategy to access analogues of an original natural bioactive flavone

Guimard, Carole Jézéquel, Gwenaëlle Askenatzis, Laurie

International audience

Uploaded on: January 19, 2024
2023 (v1)

Journal article

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Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein

Jézéquel, Gwenaëlle Rampal, Céline Guimard, Carole

Schweinfurthins (SWs) are naturally occurring prenylated stilbenes with promising anticancer properties. They act through a novel mechanism of action similar to that of other families of natural compounds. Their known target, oxysterol-binding protein (OSBP), plays a crucial role in controlling the intracellular distribution of cholesterol. We...

Uploaded on: November 25, 2023