2001 (v1)
Publication
The pathophysiological model of schizophrenia based on an NMDAR-mediated glutamate hypofunction was raised by the psychotomimetic effects induced by administration of non-competitive NMDAR antagonists. Animal models further supported this hypothesis. Functional NMDARs are composed of the ubiquitous NR1 subunit and one of four NR2 subunits. The...
Uploaded on: May 13, 2023