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HÄRING , Dieter A

Last name: HÄRING

First name: Dieter A

2016 (v1)

Publication

Metadata-only

Inclusion of brain volume loss in a revised measure of 'no evidence of disease activity' (NEDA-4) in relapsing-remitting multiple sclerosis

Kappos, Ludwig De Stefano, Nicola Freedman, Mark S

'No evidence of disease activity' (NEDA), defined as absence of magnetic resonance imaging activity (T2 and/or gadolinium-enhanced T1 lesions), relapses and disability progression ('NEDA-3'), is used as a comprehensive measure of treatment response in relapsing multiple sclerosis (RMS), but is weighted towards inflammatory activity. Accelerated...

Uploaded on: May 13, 2023
2018 (v1)

Publication

Metadata-only

Brain atrophy and disability worsening in primary progressive multiple sclerosis: insights from the INFORMS study

Miller, David H Lublin, Fred D Sormani, Maria Pia

Objective: To investigate the relationship between brain volume and disability worsening over ≥3 years in the natural history of primary progressive multiple sclerosis using data from the placebo group of the INFORMS trial (n = 487; clinicaltrials.gov NCT00731692). Methods: Magnetic resonance imaging scans were collected annually. Brain volume...

Uploaded on: April 14, 2023