H

J

HAIECH , Jacques

Last name: HAIECH

First name: Jacques

July 4, 2019 (v1)

Publication

Metadata-only

The adaptors Grb10 and Grb14 are calmodulin-binding proteins

García Palmero, Irene Pompas Veganzones, Noemí Villalobo Polo, Eduardo

We identified the Grb7 family members, Grb10 and Grb14, as Ca2+-dependent CaM-binding proteins using Ca2+-dependent CaM-affinity chromatography as we previously did with Grb7. The potential CaM-binding sites were identified and experimentally tested using fluorescent-labeled peptides corresponding to these sites. The apparent affinity constant...

Uploaded on: December 4, 2022
February 2018 (v1)

Journal article

Metadata-only

Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness

Bogeas, Alexandra Morvan-Dubois, Ghislaine El-Habr, Elías

Although a growing body of evidence indicates that phenotypic plasticity exhibited by glioblastoma cells plays a central role in tumor development and post-therapy recurrence, the master drivers of their aggressiveness remain elusive. Here we mapped the changes in active (H3K4me3) and repressive (H3K27me3) histone modifications accompanying the...

Uploaded on: December 4, 2022