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HAMAMOTO , Shin

Last name: HAMAMOTO

First name: Shin

2014 (v1)

Publication

Metadata-only

The phosphoinositide PI(3,5)P2 mediates activation of mammalian but not plant TPC proteins: Functional expression of endolysosomal channels in yeast and plant cells

Boccaccio, Anna Scholz-Starke, Joachim Hamamoto, Shin

Two-pore channel proteins (TPC) encode intracellular ion channels in both animals and plants. In mammalian cells, the two isoforms (TPC1 and TPC2) localize to the endo-lysosomal compartment, whereas the plant TPC1 protein is targeted to the membrane surrounding the large lytic vacuole. Although it is well established that plant TPC1 channels...

Uploaded on: April 14, 2023