International audience
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August 2018 (v1)Journal articleUploaded on: December 4, 2022
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May 1, 2021 (v1)Journal article
Pulmonary arterial hypertension (PAH) refers to a set of heterogeneous vascular diseases defined by elevation of pulmonary arterial pressure (PAP) and pulmonary vascular resistance (PVR), leading to right ventricular (RV) remodeling and often death. Early increases in pulmonary artery stiffness in PAH drive pathogenic alterations of pulmonary...
Uploaded on: December 4, 2022 -
October 22, 2021 (v1)Journal article
A network dependency platform was generated to define a landscape of cancer drug mechanisms in pulmonary hypertension.
Uploaded on: December 4, 2022 -
October 22, 2021 (v1)Journal article
A network dependency platform was generated to define a landscape of cancer drug mechanisms in pulmonary hypertension.
Uploaded on: February 22, 2023 -
October 22, 2021 (v1)Journal article
Cancer therapies are being considered for treating rare noncancerous diseases like pulmonary hypertension (PH), but effective computational screening is lacking. Via transcriptomic differential dependency analyses leveraging parallels between cancer and PH, we mapped a landscape of cancer drug functions dependent upon rewiring of PH gene...
Uploaded on: December 3, 2022