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HARAJLY , Mohamad

Last name: HARAJLY

First name: Mohamad

February 1, 2016 (v1)

Journal article

Metadata-only

p53 Restoration in Induction and Maintenance of Senescence: Differential Effects in Premalignant and Malignant Tumor Cells

Harajly, Mohamad Zalzali, Hasan Nawaz, Zafar

The restoration of p53 has been suggested as a therapeutic approach in tumors. However, the timing of p53 restoration in relation to its efficacy during tumor progression still is unclear. We now show that the restoration of p53 in murine premalignant proliferating pineal lesions resulted in cellular senescence, while p53 restoration in...

Uploaded on: December 3, 2023