H

J

HARINGMAN , Jasper J.

Last name: HARINGMAN

First name: Jasper J.

2018 (v1)

Publication

Metadata-only

RELAx - REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: Protocol for a randomized controlled trial

Algera, Anna Geke Pisani, Luigi Bergmans, Dennis C. J.

Background: Evidence for benefit of high positive end-expiratory pressure (PEEP) is largely lacking for invasively ventilated, critically ill patients with uninjured lungs. We hypothesize that ventilation with low PEEP is noninferior to ventilation with high PEEP with regard to the number of ventilator-free days and being alive at day 28 in...

Uploaded on: March 27, 2023
2018 (v1)

Publication

Metadata-only

Effect of on-demand vs routine nebulization of acetylcysteine with salbutamol on ventilator-free days in intensive care unit patients receiving invasive ventilation: A randomized clinical trial

Van Meenen, David M. P. Van Der Hoeven, Sophia M. Binnekade, Jan M.

IMPORTANCE: It remains uncertain whether nebulization of mucolytics with bronchodilators should be applied for clinical indication or preventively in intensive care unit (ICU) patients receiving invasive ventilation. OBJECTIVE: To determine if a strategy that uses nebulization for clinical indication (on-demand) is noninferior to one that uses...

Uploaded on: April 14, 2023