H

J

HARTL , Johannes

Last name: HARTL

First name: Johannes

2020 (v1)

Journal article

Metadata-only

Slow Growth and Increased Spontaneous Mutation Frequency in Respiratory Deficient afo1- Yeast Suppressed by a Dominant Mutation in ATP3

Li, Jing Rinnerthaler, Mark Hartl, Johannes

A yeast deletion mutation in the nuclear-encoded gene, AFO1, which codes for a mitochondrial ribosomal protein, led to slow growth on glucose, the inability to grow on glycerol or ethanol, and loss of mitochondrial DNA and respiration. We noticed that afo1- yeast readily obtains secondary mutations that suppress aspects of this phenotype,...

Uploaded on: December 3, 2022