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HIDALGO-FIGUEROA , María

Last name: HIDALGO-FIGUEROA

First name: María

January 14, 2015 (v1)

Publication

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GDNF Is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after Injury of the nigrostriatal pathway

Hidalgo-Figueroa, María Bonilla Jiménez, Sonia Gutiérrez, Francisco

Glial cell line-derived neurotrophic factor (GDNF) is absolutely required for survival of dopaminergic (DA) nigrostriatal neurons and protect them from toxic insults. Hence, it is a promising, albeit experimental, therapy for Parkinson's disease (PD). However, the source of striatal GDNF is not well known. GDNF seems to be normally synthesized...

Uploaded on: March 27, 2023
January 14, 2015 (v1)

Publication

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Age-mediated transcriptomic changes in adult mouse substantia nigra

Gao Chen, Lin Hidalgo-Figueroa, María Escudero Cuadrado, Luis María

Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson's disease (PD). Until now, molecular mechanisms behind SNpc aging have not been fully investigated using high throughput techniques. Here, we show early signs of aging in SNpc, which are more evident than in ventral tegmental area...

Uploaded on: March 27, 2023
January 16, 2015 (v1)

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Neuroprotection in Parkinson's Disease

Pascual Bravo, Alberto Villadiego Luque, Francisco Javier Hidalgo-Figueroa, María

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Uploaded on: December 4, 2022