IGF1 plays a key role in the development and growth of multiple tumors and in the prevention of apoptosis. In melanoma cells, IGF1 has been shown to mediate resistance to anoikis-induced apoptosis. However, the effect of IGF1 on other proapoptotic stimuli has never been reported. Further, the molecular mechanisms by which IGF1 mediates its...
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June 2008 (v1)Journal articleUploaded on: December 4, 2022
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May 13, 2003 (v1)Journal article
Embryonic stem (ES) cell lines can be expanded indefinitely in culture while maintaining their potential to differentiate into any cell type. During embryonic development, the skin forms as a result of reciprocal interactions between mesoderm and ectoderm. Here, we report the in vitro differentiation and enrichment of keratinocytes from murine...
Uploaded on: December 4, 2022 -
September 1, 2005 (v1)Journal article
International audience
Uploaded on: December 4, 2022