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HOONING , Maartje

Last name: HOONING

First name: Maartje

October 2020 (v1)

Journal article

Metadata-only

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

Barnes, Daniel Rookus, Matti Mcguffog, Lesley

We assessed the associations between population-based polygenic risk scores (PRS) for breast (BC) or epithelial ovarian cancer (EOC) with cancer risks for BRCA1 and BRCA2 pathogenic variant carriers. Methods: Retrospective cohort data on 18,935 BRCA1 and 12,339 BRCA2 female pathogenic variant carriers of European ancestry were available. Three...

Uploaded on: December 4, 2022