H

H

HOPE , Hannah

Last name: HOPE

First name: Hannah

Institution: UCA

Links

September 2008 (v1)

Journal article

Metadata-only

Activation of Rac1 by the Guanine Nucleotide Exchange Factor Dck1 Is Required for Invasive Filamentous Growth in the Pathogen Candida albicans.

Hope, Hannah Bogliolo, Stéphanie Arkowitz, Robert A

Rho G proteins and their regulators are critical for cytoskeleton organization and cell morphology in all eukaryotes. In the opportunistic pathogen Candida albicans, the Rho G proteins Cdc42 and Rac1 are required for the switch from budding to filamentous growth in response to different stimuli. We show that Dck1, a protein with homology to the...

Uploaded on: December 4, 2022
April 27, 2010 (v1)

Journal article

Metadata-only

The Candida albicans ELMO homologue functions together with Rac1 and Dck1, upstream of the MAP Kinase Cek1, in invasive filamentous growth.

Hope, Hannah Schmauch, Christian Arkowitz, Robert A

Summary Regulation of Rho G-proteins is critical for cytoskeletal organization and cell morphology in all eukaryotes. In the human opportunistic pathogen Candida albicans, Rac1 and its activator Dck1, a member of the CED5, Dock180, myoblast city family of guanine nucleotide exchange factors, are required for the budding to filamentous...

Uploaded on: December 3, 2022