HORIKAWA , Reiko

Introduction: Mutations in PTPN11 are associated with Noonan syndrome (NS). Although the effectiveness of growth hormone therapy (GHT) in treating short stature due to NS has been previously demonstrated, the effect of PTPN11 mutation status on the long-term outcomes of GHT remains to be elucidated. Methods: This analysis included pooled data...

KIGS is a large, international database (1987-2012) of children treated with recombinant human growth hormone (rhGH) in real-world settings.