This article reviews the role of emerging biologic drugs for the treatment of rheumatoid arthritis (RA). Besides anti-tumor necrosis factor (TNF)-alpha and anti-interleukin (IL)-1 agents (Infliximab, Adalimurnab, Etanercept and Anakinra) whose clinical efficacy is now established, new drugs have been proposed for the therapy of rheumatoid...
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2005 (v1)PublicationUploaded on: December 2, 2022
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1995 (v1)Publication
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1997 (v1)Publication
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1994 (v1)Publication
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2001 (v1)Publication
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2017 (v1)Publication
Antiphospholipid antibody syndrome (APS) is an autoimmune acquired thrombophilia characterized by recurrent thrombosis and pregnancy morbidity in the presence of antiphospholipid antibodies (aPL). APS can be primary, if it occurs in the absence of any underlying disease, or secondary, if it is associated with another autoimmune disorder, most...
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2002 (v1)Publication
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2006 (v1)Publication
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2000 (v1)Publication
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2011 (v1)Publication
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2009 (v1)Publication
Vaccino peptidico antitumorale
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2003 (v1)Publication
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2000 (v1)Publication
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1995 (v1)Publication
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2016 (v1)Publication
Cilostazol is a selective inhibitor of phosphodiesterase-III with antiplatelet, antithrombotic and vasodilating properties. The aim of our study was to evaluate the effect of the drug on vasculopathy and Raynaud's phenomenon (RP), in a series of patients with systemic sclerosis (SSc), before and after cilostazol treatment. Twenty-one...
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1995 (v1)Publication
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2003 (v1)Publication
There is convincing evidence that soluble HLA-A,-B,-C (sHLA-A,-B,-C) and soluble HLA-G (sHLA-G) antigens can induce apoptosis in CD8(+) activated T cells although there is scanty and conflicting information about the mechanism(s) by which sHLA-A,-B,-C antigens and sHLA-G antigens induce apoptosis. In this study we have compared the...
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2009 (v1)Publication
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2008 (v1)Publication
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2000 (v1)Publication
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2007 (v1)Publication
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1998 (v1)Publication
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