IRENE VASSALLO

We recently described Rolly Protein (ROLP), a small protein synthesized by substrate-adherent cells in a broad range of tissues. In a first set of experiments performed taking advantage of bone forming tibial cartilage as an experimental model we showed that ROLP transcription is associated to cells in an active proliferation state, whereas its...

Alternative splicing generates protein isoforms that are conditionally or differentially expressed in specific tissues. Discovery of factors that control alternative splicing might clarify the molecular basis of biological and pathological processes. We found that IL1-α dependent upregulation of 38A, a small RNA polymerase III-transcribed...