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IEZZI , Giandomenica

Last name: IEZZI

First name: Giandomenica

July 15, 2006 (v1)

Journal article

Metadata-only

Lymph node resident rather than skin-derived dendritic cells initiate specific T cell responses after Leishmania major infection.

Iezzi, Giandomenica Fröhlich, Anja Ernst, Bettina

Langerhans cells have been thought to play a major role as APCs for induction of specific immune responses to Leishmania major. Although their requirement for control of infection has been challenged recently, it remains unclear whether they can transport Ag to lymph nodes and promote initiation of T cell responses. Moreover, the role of dermal...

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