Most patients with idiopathic REM sleep behavior disorder (iRBD) will develop an overt alpha-synucleinopathy over time, with a rate of phenoconversion of 73.5% after 12 years from diagnosis. Several markers of phenoconversion were identified; however, most studies investigated biomarkers separately, with retrospective study designs, in small...
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2022 (v1)PublicationUploaded on: February 13, 2024
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2023 (v1)Publication
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Uploaded on: February 13, 2024 -
2024 (v1)Publication
Background and objectives: Narcolepsy type 1 (NT1) is still largely underdiagnosed or diagnosed too late in children. Difficulties in obtaining rapid and reliable diagnostic evaluations of the condition in clinical practice partially explain this problem. Predictors of NT1 include cataplexy and sleep-onset REM periods (SOREMPs), documented...
Uploaded on: January 31, 2024 -
2020 (v1)Publication
Ageing of the global population represents a challenge for national healthcare systems and healthcare professionals, including medico-legal experts, who assess personal damage in an increasing number of older people. Personal damage evaluation in older people is complex, and the scarcity of evidence is hindering the development of formal...
Uploaded on: February 14, 2024