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ISSAOUI , Hussein

Last name: ISSAOUI

First name: Hussein

December 31, 2022 (v1)

Journal article

Metadata-only

IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response

Martinez-Turtos, Adriana Paul, Rachel Grima-Reyes, Manuel

IRE1α is one of the three ER transmembrane transducers of the Unfolded Protein Response (UPR) activated under endoplasmic reticulum (ER) stress. IRE1α activation has a dual role in cancer as it may be either pro- or anti-tumoral depending on the studied models. Here, we describe the discovery that exogenous expression of IRE1α, resulting in...

Uploaded on: December 3, 2022