J

S

JOSHI , S.

Last name: JOSHI

First name: S.

October 23, 2023 (v1)

Publication

Metadata-only

Association of high microvessel alpha(v)beta(3) and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126

Erdreich-Epstein, A. Singh, AR Joshi, S.

Neuroblastoma (NB) is the most common extracranial solid tumor in children. Our previous studies showed that the angiogenic integrin αvβ3 was increased in high-risk metastatic (stage 4) NB compared with localized neuroblastomas. Herein, we show that integrin αvβ3 was expressed on 68% of microvessels in MYCN-amplified stage 3 neuroblastomas, but...

Uploaded on: November 25, 2023