La formacion del Sistema Nervioso Central (SNC) y la diferenciacion de neuronas, celulas gliales y otros tipos celulares que lo conforman, son procesos esenciales que implican un gran número de eventos celulares que tienen lugar durante el desarrollo en los eucariotas superiores. Estos eventos incluyen la activacion de varias rutas de...
-
May 8, 2018 (v1)PublicationUploaded on: March 27, 2023
-
August 22, 2017 (v1)Publication
Paired box 4 (PAX4) is a key factor in the generation of insulin producing β-cells during embryonic development. In adult islets, PAX4 expression is sequestered to a subset of β-cells that are prone to proliferation and more resistant to stress-induced apoptosis. The importance of this transcription factor for adequate pancreatic islets...
Uploaded on: March 27, 2023