K

KAPLAN S.

Last name: KAPLAN S.

1995 (v1)

Publication

Metadata-only

Ig h and l chain variable region gene sequence analyses of twelve synovial tissue-derived b cell lines producing iga, igg, and igm rheumatoid factors structure/function comparisons of antigenic specificity, v gene sequence, and IG isotype

Jain R. I. Fais F. Kaplan S.

In the present study, the complete sequences of the Ig H and L chain variable region genes of twelve RF+ B cell lines from two patients with RA were analyzed. Seven of the RF-producing B cells used VH3 family genes, four used VH4 genes, and one a VH1 gene. All but two of the cell lines expressing VH3 genes utilized different family members;...

Uploaded on: May 12, 2023