KARAMAOUN , Cyril

Mammals have a high metabolism that produces heat proportionally to the power 3/4 of their mass at rest. Any excess of heat has to be dissipated in the surrounding environment to prevent overheating. Most of that dissipation occurs through the skin, but the efficiency of that mechanism decreases with the animal's mass. The role of the other...

A secondary function of the respiratory system of the mammals is, during inspiration, to heat the air to body temperature and to saturate it with water before it reaches the alveoli. Relying on a mathematical model, we propose a comprehensive analysis of this function, considering all the terrestrial mammals (spanning six orders of magnitude of...

A secondary function of the respiratory system of the mammals is, during inspiration, to heat the air to body temperature and to saturate it with water before it reaches the alveoli. Relying on a mathematical model, we propose a comprehensive analysis of this function, considering all the terrestrial mammals (spanning six orders of magnitude of...

A model of optimal control of ventilation has recently been developed for humans. This model highlights the importance of the localization of the transition between a convective and a diffusive transport of respiratory gas. This localization determines how ventilation should be controlled in order to minimize its energetic cost at any metabolic...

On the bronchi walls, the bronchial mucus forms a thin layer that protects the lung by capturing inhaled pollutants. Due to the curvature of its interface with air, the layer is submitted to curvature effects that interact with its rheology. Based on lubrication theory and 3D simulations, we show that these effects might move overthick mucus...

On the bronchi walls, the bronchial mucus forms a thin layer that protects the lung by capturing inhaled pollutants. Due to the curvature of its interface with air, the layer is submitted to curvature effects that interact with its rheology. Based on lubrication theory and 3D simulations, we show that these effects might move overthick mucus...

The mucus on the bronchial wall forms a thin layer of non-Newtonian fluid, protecting the lungs by capturing inhaled pollutants. Due to the corrugation of its interface with air, this layer is subject to surface tension forces that affect its rheology. This physical system is analyzed using lubrication theory and three-dimensional simulations....

Lining the bronchi in the lung, the mucus constitutes a protective layer from harmful pathogens and particles. Its displacement due to the coordinated beating of the bronchial epithelium cilia contributes to its clearance from the lung. As this mucociliary clearance is impaired in numerous pathologies, a comprehensive understanding of this...

International audience

Introduction: Conditioning of air during respiration occurs in the upper airways, but also in the bronchi (McFadden et al., 1985). Because it is related to the evaporation of the water contained in the mucus (Karamaoun et al., 2018), it could affect its dynamics, but also the body water and thermal balance.Aim and objectives: To assess...

In healthy subjects, at low minute ventilation (V̇E) during physical exercise, the water content and the temperature of the airways are well regulated. However, with the increase in V̇E, the bronchial mucosa becomes dehydrated and epithelial damage occurs. Our goal was to demonstrate the correspondence between the ventilatory threshold inducing...

In healthy subjects, at low minute ventilation (V̇E) during physical exercise, the water content and the temperature of the airways are well regulated. However, with the increase in V̇E, the bronchial mucosa becomes dehydrated and epithelial damage occurs. Our goal was to demonstrate the correspondence between the ventilatory threshold inducing...

International audience