KARVOUNIARI , Dora

Doctoral

International audience

Retinal waves are spontaneous waves of spiking activity observed in the retina, during development only,playing a central role in shaping the visual system and retinal circuitry. Understanding how these waves areinitiated and propagate in the retina could enable one to control, guide and predict them in the in vivo adultretina as inducing them...

International audience

International audience

Retinal waves are spontaneous bursts of activity propagating in the developping retina and thought to play a central role in shaping the visual system and retinal circuitry. They first occur at early embryonic stages of development and gradually disappear upon maturation. Understanding their generating mechanisms may help to control and use...

Retinal waves are spontaneous bursting activity propagating in the developping retina until vision is functional. In this work we propose a biophysical modelling of the mechanism that generates the spontaneous intrinsic cell-autonomous rhythmic bursting in Starbust Amacrine Cells (SACs), observed experimentally in [1] which is directly linked...

International audience

International audience

International audience

Retinal waves are bursts of activity occurring spontaneously in the developing retina of vertebrate species, contributing to the shaping of the visual system organization. They are characterized by localized groups of neurons becoming simultaneously active, initiated at random points. Based on our previous modelling work [1], we now propose a...

Retinal waves are bursts of activity occurring spontaneously in the developing retina of vertebrate species, contributing to the shaping of the visual system organization and disappear short after birth. Waves during development are a transient process which evolves dynamically exhibiting different features. Based on our previous modelling work...

International audience

In the early retina, spontaneous collective network activity emerges as propagating waves, playing a central role in shaping the visual system. Elucidating how the characteristics of such waves depend on biophysical parameters, would help us understand the underlying mechanisms of spatio-temporal patterns formation in the developing retina and...

Retinal waves are spontaneous bursting activity propagating in the developping retina until vision is functional. In this work we propose a biophysical modelling of the mechanism that generates the spontaneous intrinsic cell-autonomous rhythmic bursting in Starbust Amacrine Cells (SACs), observed experimentally in [1] which is directly linked...

Retinal waves are bursts of activity occurring spontaneously in the developing retina of vertebrate species, contributing to the shaping of the visual system organization and disappear short after birth. Waves during development are a transient process which evolves dynamically exhibiting different features. Based on our previous modelling work...

International audience

During early development, waves of activity propagate across the retina and play a key role in the proper wiring of the early visual system. During a particular phase of the retina development (stage II) these waves are triggered by a transient network of neurons, called Starburst Amacrine Cells (SACs), showing a bursting activity which...

International audience