KHOODEERAM , Rajeev

We present a formal model of the regulation of the energetic metabolism in eukaryotic cells. The main originality of this model is to consider explicitly an abstraction of the main metabolic processes that pilot this metabolism, thereby greatly reducing the number of variables in the model. Moreover, the modelling framework proposed by Réné...

International audience

Adaptation of metabolism is a response of many eukaryotic cells to nutrient heterogeneity in the cell microenvironment. One of these adaptations is the shift from respiratory to fermentative metabolism, also called the Warburg/Crabtree effect. It is a response to a very high nutrient increase in the cell microenvironment, even in the presence...

Adaptation of metabolism is a response of many eukaryotic cells to nutrient heterogeneity in the cell microenvironment. One of these adaptations is the shift from respiratory to fermentative metabolism, also called the Warburg/Crabtree effect. It is a response to a very high nutrient increase in the cell microenvironment, even in the presence...