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KOOTAR , Scherazad

Last name: KOOTAR

First name: Scherazad

March 24, 2017 (v1)

Publication

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Importance of glucocorticoid receptors in the physiopathology of Alzheimer's disease

Kootar, Scherazad

Strong evidence shows that oligomeric forms of the amyloid-ß peptide (oAß) cause synapse dysfunction promoting loss of hippocampus-dependent memories in the early phase of Alzheimer's disease (AD). AD is also associated with Hypothalamus-Pituitary-Adrenal (HPA) axis dysfunction which results in an increase of glucocorticoids (CORT) activating...

Uploaded on: February 28, 2023
October 2018 (v1)

Journal article

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Identification of an acute functional cross-talk between amyloid-β and glucocorticoid receptors at hippocampal excitatory synapses

Kootar, Scherazad Frandemiche, Marie-Lise Dhib, Gihen

International audience

Uploaded on: December 4, 2022
October 2015 (v1)

Journal article

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η-Secretase processing of APP inhibits neuronal activity in the hippocampus

Willem, Michael Tahirovic, Sabina Busche, Marc Aurel

International audience

Uploaded on: December 4, 2022