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KOUBI , Myriam

Last name: KOUBI

First name: Myriam

2022 (v1)

Journal article

Metadata-only

Aberrant DNA methylation impacts HOX genes expression in bone marrow mesenchymal stromal cells of myelodysplastic syndromes and de novo acute myeloid leukemia

Roux, Benjamin Picou, Frederic Debeissat, Christelle

DNA methylation, a major biological process regulating the transcription, contributes to the pathophysiology of hematologic malignancies, and hypomethylating agents are commonly used to treat myelodysplastic syndromes (MDS) and acute myeloid leukemias (AML). In these diseases, bone marrow mesenchymal stromal cells (MSCs) play a key supportive...

Uploaded on: December 3, 2022