KOZLOV , Vladimir

Congenital Anomalies of Kidneys and Urinary Tract (CAKUT) are a group of birth defects that arise from defects in the developmental program of organ development and are frequently found in human patients. Sox11 is a member of SoxC family of transcription factors, which plays an important role in the development of various organs in vertebrates....

Congenital abnormalities of the kidney and urinary tract (CAKUT) are a highly diverse group of diseases that together belong to the most common abnormalities detected in the new-born child. Consistent with this diversity, CAKUT are caused by mutations in a large number of genes and present a wide spectrum of phenotypes. In this review, we will...