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KRAL , Rosana

Last name: KRAL

First name: Rosana

May 15, 2010 (v1)

Journal article

Metadata-only

Identification of a lysine-rich region of Fas as a raft nanodomain targeting signal necessary for Fas-mediated cell death.

Rossin, Aurélie Kral, Rosana Lounnas, Nadia

Fas interaction at the plasma membrane with its lipid and protein environment plays a crucial role in the early steps of Fas signalling induced by Fas ligand binding. Particularly, Fas localisation in the raft nanodomains, ezrin-mediated interaction with the actin cytoskeleton and subsequent internalization are critical steps in Fas-mediated...

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